Current Development in Theory and Applications of Wavelets
Volume 4, Issue 2, Pages 153 - 183
(August 2010)
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QUANTITATIVE IMAGE ENHANCEMENT BY PARTIAL VOLUME EFFECT CORRECTION WITH CONTINUOUS WAVELET TECHNIQUE IN SMALL ANIMAL PET IMAGING
Lahcen Arhjoul, Otman Sarrhini and M’hamed Bentourkia
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Abstract:
The underestimation of the emitted radioactivity in small tissue structures measured with positron emission tomography (PET) unfortunately requires correction for the partial volume effect (PVE) prior to image analysis. Meanwhile, the continuous wavelet transform (CWT) has the potential to isolate signals of small structures from their environments, and to determine each structure by its width and position in PET images. Using CWT analysis and recovery coefficients (RC), we report a new approach to correct for PVE in phantom and in rat PET images, regardless of the shape of the structures. The results show a full recovery in image intensity in the phantom small hot cylinders, and similarly in rats with two small tumors. On the other hand, metabolic rate of glucose (MRG) was assessed in rat images before and after PVE correction, and the MRG values were significantly increased after PVE correction. |
| Keywords and phrases: partial volume effect correction, PET, recovery coefficients, continuous wavelet transform. |
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