Introduction. Complete tooth irrigation during cleaning and shaping eliminates the microorganisms that cannot be removed using physical methods. The purpose of this study was to compare the effects of chlorhexidine and sodium hypochlorite on reducing pain and swelling at different times after necrotic pulp treatment.

Method. In this cross-sectional descriptive study, 60 patients (2 groups of 30 subjects) with one maxilla single-canal tooth with necrotic pulp were examined. The teeth were prepared using rotary files with 0.2% digluconate chlorhexidine and using 2.5% sodium hypochlorite for irrigation. Patients’ pain was followed up to 72 hours. The patients checked their pain score on the sheet given to them and swelling was evaluated in two steps. Then the data was analyzed in SPSS, version 19, software.

Results. The results showed that the frequency of pain and swelling in 0.2% chlorhexidine and 2.5% sodium hypochlorite, not only showed no significant differences over time, but also there were no significant postoperative differences between the two irrigant at 24, 48 and 72 hours. The results also showed that sodium hypochlorite and chlorhexidine had a similar effect on pain and swelling after endodontic therapy.

Conclusion. Given the persistent effect of chlorhexidine after treatment and no toxic effects on periapical tissue, it is suggested to replace this irrigant with sodium hypochlorite pulp in the treatment of root in teeth with necrotic pulp.

chlorhexidine, sodium hypochlorite, irrigants, flare-up.

Received: February 25, 2020; Accepted: March 16, 2020; Published: January 28, 2021

How to cite this article: Fatemeh Rashki Ghaleno, Abolhasan Bakhtyari, Tahere Aliabadi and Mansour Mirballouch Zehi, Comparison of the effect of chlorhexidine and sodium hypochlorite as an intracanal irrigant on flare-up after endodontic therapy in teeth with necrotic pulp, JP Journal of Biostatistics 18(1) (2021), 99-109. DOI: 10.17654/BS018010099

This Open Access Article is Licensed under Creative Commons Attribution 4.0 International License

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